Which of the following is a sign of general cooling of the body?

Hypothermia is characterized by a significant decrease in body temperature due to prolonged exposure to cold environments. This condition occurs when the body's heat loss exceeds its heat production, leading to a core body temperature that falls below the normal range, which is typically around 98.6°F (37°C). Symptoms of hypothermia can include shivering, confusion, sluggishness, and ultimately, if left untreated, unconsciousness and death.

In contrast to the other choices, which represent different conditions associated with heat (frostbite is related to localized cold injuries, hyperthermia indicates excessive heat in the body, and heat stroke is a severe form of hyperthermia), hypothermia specifically signifies a general cooling of the body. Understanding these differences is crucial for identifying and responding appropriately to varying temperature-related medical emergencies.